What the worst thing about smoking weed? I've been working with teens for 10 years, I have a masters in marriage and family therapy from U.M. and I've been involved in various research studies focusing on teenagers with substance abuse issues. So here is my professional opinion for what it's worth. This is the worst thing about weed: When you're high it makes it OK to be bored. It makes your anger, anxiety, shyness, shame and sadness go away for a while. You get hungry, you laugh, food tastes great, you sleep, you wake up feeling strung out and a little less sensitive to life's troubles. It's an escape from the painful and the mundane. And it works immediately, at least for a while. In short, smoking weed becomes how you deal with life's problems.